Pizza Places in Port St. Lucie, FL

Pizza in Port St. Lucie at a glance

• Pizza is the largest food category in Port St. Lucie.
• Its 10.1% share compares with 6.3% across the 506 cities in this guide, so Port St. Lucie leans toward pizza.
• Of the 55 listed below, 32 are independent and 23 belong to chains; 51 list a website.

Pizza Places in Port St. Lucie

• Papa Johns Pizza
  Restaurant · Pizza · Chain · 1683 St Lucie W Blvd
• A Slice of Heaven
  Restaurant · Pizza · 10075 S Federal Hwy #1
• Sweet Basil Italiano
  Restaurant · Pizza · 291 SE Port St Lucie Blvd
• Roma Pizza and Restaurant
  Restaurant · Pizza · 2753 SE Morningside Blvd
• Blaze Pizza
  Restaurant · Pizza · Chain · 11175 SW Village Pkwy
• Alfonso's Pizza & Pasta
  Restaurant · Pizza · 2740 Brigantine Pl
• Big Apple Pizza & Pasta
  Restaurant · Pizza · Chain · 1310 SW Bayshore Blvd
• Dangelos Pizza & Subs
  Restaurant · Pizza · 1018 SW Bayshore Blvd
• Domino's
  Restaurant · Pizza · Chain · 1341 Sw Gatlin Blvd
• Estella's Pizzeria
  Restaurant · Pizza · 1276 SW California Blvd
• Little Caesars Pizza
  Restaurant · Pizza · Chain · 4019 SW Port St Lucie Blvd
• Little Caesars Pizza
  Restaurant · Pizza · Chain · 1099 SE Port St Lucie Blvd Ste 100
• Pizza Hut
  Restaurant · Pizza · Chain · 1014 SE Port St. Lucie Blvd. St. Lucie
• Tavola Pizza
  Restaurant · Pizza · 1672 SE Port St Lucie Blvd
• Domino's
  Restaurant · Pizza · Chain · 123 Cashmere Blvd
• Big Apple Pizza & Pasta
  Restaurant · Pizza · 9128 S US Highway 1
• All-American Pizzeria
  Restaurant · Pizza · 222 SW Port St Lucie Blvd
• Big Apple Pizza & Pasta
  Restaurant · Pizza · Chain · 872 St Lucie W Blvd
• Goodfella's Pizza
  Restaurant · Pizza · Chain · 148 NW California Blvd
• Pizza Hut
  Restaurant · Pizza · Chain · 1224 SW Gatlin Blvd
• Big Apple Pizza
  Restaurant · Pizza · 2856 SW Port St Lucie Blvd
• Papa John's Pizza
  Restaurant · Pizza · Chain · 231 SW Port St Lucie Blvd
• Domino's Pizza
  Restaurant · Pizza · Chain · 300 SW Port St Lucie Blvd
• Frank & Al's Pizzeria
  Restaurant · Pizza · 2088 NW Courtyard Cir
• Anthony's Pizza
  Restaurant · Pizza · 253 SW Port St Lucie Blvd
• Panariello's of Port St Lucie
  Restaurant · Pizza · 466 SW Port St Lucie Blvd, 466 SW Port St Lucie Blvd
• Papa Johns
  Restaurant · Pizza · Chain · 10340 sw discovery way
• Francesca's Pizza
  Restaurant · Pizza · 3961 SW Port St Lucie Blvd
• Marco's Pizza
  Restaurant · Pizza · Chain · 916 SW Gatlin Blvd
• 3rd Avenue Pizza and Pasta
  Restaurant · Pizza · 8900 S US-1
• Pizza Hut Express
  Restaurant · Pizza · Chain · 10720 SW Vlg Pkwy
• Antonio's Pizza
  Restaurant · Pizza · 741 NW Airoso Blvd
• Fratelli's Pizzeria
  Restaurant · Pizza · 2987 SW Port St Lucie Blvd
• Cam's Pizzeria
  Restaurant · Pizza · 2987 SW Port St Lucie Blvd
• Don's Pizzeria
  Restaurant · Pizza · 222 Sw Port St Lucie Blvd Unit 106
• Lombardi's Restaurant
  Restaurant · Pizza · 1042 SE Port St Lucie Blvd
• Alfonso Pizza
  Restaurant · Pizza · 1550 SE Floresta Dr
• Bobby's Pizza
  Restaurant · Pizza · 6514 NW Selvitz Rd
• Domino's
  Restaurant · Pizza · Chain · 1675 Nw St Lucie West Blvd
• Labby's Pizza & Pasta
  Restaurant · Pizza · 3961 SW Port St Lucie Blvd
• Little Caesars
  Restaurant · Pizza · Chain · 1471 SW Gatlin Blvd
• MOD Pizza
  Restaurant · Pizza · Chain · 1401 NW Saint Lucie West Blvd
• Prisco's Pizza
  Restaurant · Pizza · 1564 SE Floresta Dr
• Scoozi Artisan Pizza
  Restaurant · Pizza · 1018 SW Bayshore Blvd
• Stevi B's Pizza
  Restaurant · Pizza · 1420 SW Saint Lucie West Blvd
• The Pizza House
  Restaurant · Pizza · 1352 SW Bayshore Blvd
• Little Italy of St Lucie
  Restaurant · Pizza · 1329 NW St Lucie W Blvd
• Pizza Hut
  Restaurant · Pizza · Chain · 1728 SW St Lucie West Blvd
• Port St. Lucie, FL - Village Parkway
  Restaurant · Pizza · Chain · 11175 SW Village Pkwy
• CiCi's Pizza Buffet
  Restaurant · Pizza · 2343 SE Federal Hwy
• Little Caesars Pizza
  Restaurant · Pizza · Chain · 1774 SW St Lucie West Blvd
• Mama's Italian Restaurant & Pizzeria
  Restaurant · Pizza · 9128 S US Highway 1
• Goodfella's Pizza
  Restaurant · Pizza · 3065 SW Port St Lucie Blvd
• Panariello Pizza & Pastery
  Restaurant · Pizza · 291 SE Port St Lucie Blvd
• PORT ST. LUCIE
  Restaurant · Pizza · Chain · 1707 NW St Lucie West Blvd Port St Lucie, FL 34986

Pizza elsewhere in Florida

Among the Florida cities in this guide, the most pizza listings are in Jacksonville (239), Miami (147), Tampa (134), Orlando (127), Fort Lauderdale (91) and Tallahassee (75).

Run a pizza spot in Port St. Lucie?

You share this list with 54 other pizza listings. The ones guests reorder from are the ones that are easy to order from directly. Servestack gives you your own ordering site with zero commission, and Studio designs the menu, flyers and posts to go with it. Run your numbers with the commission savings calculator.

Place data from the Overture Maps Foundation (overturemaps.org), which includes data from Meta, Microsoft and Foursquare, used under the CDLA Permissive 2.0 and Apache 2.0 licenses. Restaurants open, close and move; check with the restaurant before you go. Data refreshed 2026-10-11.