American Restaurants in Syracuse, NY

American in Syracuse at a glance

• American is the 6th largest food category in Syracuse, after bars and coffee shops and cafes.
• Its 4.2% share compares with 3.8% across the 506 cities in this guide, close to the national pattern.
• Of the 28 listed below, 26 are independent and 2 belong to chains; 26 list a website.

American Restaurants in Syracuse

• 110 Grill
  Restaurant · American · 9090 Destiny USA Dr
• Funk n' Waffles
  Restaurant · American · 727 S Crouse Ave
• Oh My Darling
  Restaurant · American · 321 S Salina St
• Eden
  Restaurant · American · 118 E Genesee St
• Riley's
  Restaurant · American · 312 Park St
• 317 @ Montgomery Street
  Restaurant · American · 317 Montgomery St
• The Cheesecake Factory
  Restaurant · American · Chain · 306 Hiawatha Blvd W Spc J - 112
• City Hall Cafe
  Restaurant · American · Chain · 300 S State St
• A Taste of Philadelphia
  Restaurant · American · 2533 James St
• Salt Restaurant and Bar
  Restaurant · American · 1060 E Genesee St
• Rachel's Restaurant
  Restaurant · American · 801 University Ave
• 201 Bistro at Wise Guys
  Restaurant · American · 201 S Salina St
• bc Restaurant
  Restaurant · American · 247 W Fayette St
• Bleu Chick
  Restaurant · American · Southern and soul food · 317 N Salina St
• Daniel Jack's Entertainment Restaurant
  Restaurant · American · 218 Walton St
• Opus Restaurant
  Restaurant · American · 218 Walton St
• Parisa
  Restaurant · American · 317 Montgomery St
• Redfield's Restaurant
  Restaurant · American · 701 E Genesee St
• Syracuse CoKitchen
  Restaurant · American · 810 N Salina St
• Toby Keith's I Love This Bar And Grill
  Restaurant · American · 306 Hiawatha Blvd W
• Ruby's Cheesesteaks & Fries
  Restaurant · American · 2812 James St
• 1060 Restaurant
  Restaurant · American · 1060 E Genesee St
• Smorols
  Restaurant · American · Avery Ave.
• Southern Flava
  Restaurant · American · Southern and soul food · 207 Jefferson st
• Salt City Eatery
  Restaurant · American · 311 Hiawatha Blvd W
• Salt City Kitchen & Catering
  Restaurant · American · 1205 Erie Blvd W
• Victoria Restaurant
  Restaurant · American · Latin American · 320 Lombard Ave
• The Canal
  Restaurant · American · Latin American · 314 W Onondaga St

American elsewhere in New York

Among the New York cities in this guide, the most american listings are in New York (1693), Buffalo (67), Rochester (55), Albany (31), Yonkers (27) and New Rochelle (16).

Run a american spot in Syracuse?

You share this list with 27 other american listings. The ones guests reorder from are the ones that are easy to order from directly. Servestack gives you your own ordering site with zero commission, and Studio designs the menu, flyers and posts to go with it. Run your numbers with the commission savings calculator.

Place data from the Overture Maps Foundation (overturemaps.org), which includes data from Meta, Microsoft and Foursquare, used under the CDLA Permissive 2.0 and Apache 2.0 licenses. Restaurants open, close and move; check with the restaurant before you go. Data refreshed 2026-10-11.