American Restaurants in Sioux Falls, SD

American in Sioux Falls at a glance

• American is the 8th largest food category in Sioux Falls, after bars and pizza.
• Its 3.6% share compares with 3.8% across the 506 cities in this guide, close to the national pattern.
• Of the 29 listed below, 20 are independent and 9 belong to chains; 26 list a website.

American Restaurants in Sioux Falls

• TC's Referee Sports Bar & Grill
  Restaurant · American · 5322 W 26th St
• Perkins Restaurant and Bakery
  Restaurant · American · Chain · 3400 S Gateway Blvd
• 22TEN Kitchen Cocktails
  Restaurant · American · 2210 W 69th St
• Harvester Kitchen by Bryan
  Restaurant · American · 196 E 6th St
• Los Paisanos
  Restaurant · American · Latin American · 802 E 10th St
• Marlin's Family Restaurant
  Restaurant · American · Chain · 3850 N Cliff Ave
• Ruby Tuesday
  Restaurant · American · Chain · 2425 S Shirley Ave
• Applebee's
  Restaurant · American · Chain · 4001 W 41st St
• Jacky's Restaurant
  Restaurant · American · Latin American · 3101 W 41st St
• Gregg's Substation and Casino
  Restaurant · American · 1000 W 41st St
• Grill 100
  Restaurant · American · 100 W 8th St
• Falls Landing Restaurant Is Now Ode To Food & Drinks!
  Restaurant · American · 200 E 8th St
• The Willows Restaurant
  Restaurant · American · 8000 E Arrowhead Parkway
• Acoustic
  Restaurant · American · 196 E 6th St Ste 101
• K Restaurant
  Restaurant · American · 401 E 8th St
• Kaladi's
  Restaurant · American · 121 S Main Ave
• TGI Friday's
  Restaurant · American · Chain · 4200 W Empire Pl
• Wild Sage Grille
  Restaurant · American · 300 Cherapa Pl Ste 102
• Vanguard Hospitality
  Restaurant · American · 350 S Main Ave Ste 403
• Perkins at 2604 W 41st Street Sioux Falls, SD
  Restaurant · American · Chain · 2604 W 41st Street
• Perkins at 3400 Gateway Blvd Sioux Falls, SD
  Restaurant · American · Chain · 3400 Gateway Blvd
• Perkins at 5835 East Arrowhead Parkway Sioux Falls, SD
  Restaurant · American · Chain · 5835 East Arrowhead Parkway
• Applebee's Grill + Bar
  Restaurant · American · Chain · 4001 W 41st St
• Jacky's Restaurant
  Restaurant · American · Latin American · 702 E 8th St
• Maple Street Cafe
  Restaurant · American · Best Western Ramkota
• Royal Fork
  Restaurant · American · 4600-4648 W Empire Pl
• Falling Water Grille
  Restaurant · American · 1211 N West Ave
• Randles Kitchen
  Restaurant · American · 114 N Indiana Ave
• Sky Dine Services
  Restaurant · American · 2801 N Jaycee Ln

American elsewhere in South Dakota

Among the South Dakota cities in this guide, the most american listings are in Rapid City (15).

Run a american spot in Sioux Falls?

You share this list with 28 other american listings. The ones guests reorder from are the ones that are easy to order from directly. Servestack gives you your own ordering site with zero commission, and Studio designs the menu, flyers and posts to go with it. Run your numbers with the commission savings calculator.

Place data from the Overture Maps Foundation (overturemaps.org), which includes data from Meta, Microsoft and Foursquare, used under the CDLA Permissive 2.0 and Apache 2.0 licenses. Restaurants open, close and move; check with the restaurant before you go. Data refreshed 2026-10-11.