American Restaurants in Mesa, AZ

American in Mesa at a glance

• American is the 9th largest food category in Mesa, after mexican and pizza.
• Its 3.2% share compares with 3.8% across the 506 cities in this guide, close to the national pattern.
• Of the 56 listed below, 39 are independent and 17 belong to chains; 52 list a website.

American Restaurants in Mesa

• Cracker Barrel
  Restaurant · American · Southern and soul food · Chain · 1007 N. Dobson Rd. Loop 202 & Dobson Rd.
• Applebee's
  Restaurant · American · Chain · 1143 N. Higley Road
• Republica Empanada
  Restaurant · American · Latin American · 204 E 1st Ave
• Applebee's
  Restaurant · American · Chain · 6259 E Southern Ave
• Board & Batten
  Restaurant · American · 4012 E Palm St
• Hope's Frybread
  Restaurant · American · 144 S Mesa Dr
• Il Vinaio
  Restaurant · American · 270 W Main St
• Little Mesa Cafe
  Restaurant · American · 3929 E Main St #33
• Red White & Brew
  Restaurant · American · 6740 E McDowell Rd #102
• Scratch Pub & Grill
  Restaurant · American · 2401 S Lansing
• The Cheesecake Factory
  Restaurant · American · Chain · 6613 E Southern Ave
• JB's Restaurant
  Restaurant · American · 6810 E Main St
• Cafe Azul
  Restaurant · American · 200 N Centennial Way
• Dobson's Restaurant
  Restaurant · American · 2155 S Dobson Rd
• Gus's World Famous Fried Chicken
  Restaurant · American · Southern and soul food · Chain · 212 W Main St
• Copper Plate American Grill and Bar
  Restaurant · American · 6033 S Sossaman Rd
• Taste of Peru | Urban Kitchen & Pisco Bar
  Restaurant · American · Latin American · 1245 W Guadalupe Road, Suite B7-B8
• Annabelle's
  Restaurant · American · 425 S Power Rd
• Applebee's
  Restaurant · American · Chain · 2032 E Baseline Rd
• Applebee's
  Restaurant · American · Chain · 2053 S. Alma School Road
• Charleston's
  Restaurant · American · Chain · 1623 S Stapley Dr
• The Buffalo Spot
  Restaurant · American · Chain · 2837 N Power Rd #104
• 1360 West Grill
  Restaurant · American · 1360 W Southern Ave
• A Savory Affair
  Restaurant · American · 156 W Main St
• Arby's
  Restaurant · American · Chain · 1937 E Southern Ave
• Buffalo Wild Wings
  Restaurant · American · Chain · 4425 E McKellips Rd
• Coco's
  Restaurant · American · 1411 S Power Rd
• Detroit Coney Cruiser
  Restaurant · American · 2655 W Guadalupe Rd
• Detroit Coney Grill
  Restaurant · American · 6555 E Southern Ave Ste 2502
• Fiiz
  Restaurant · American · 4202 E Main St
• G.O.A.T. Restaurant & Bar
  Restaurant · American · 6321 S Ellsworth Rd
• Jerrys Restaurant
  Restaurant · American · 1976 W Southern Ave
• Julie's Chicken & Waffles
  Restaurant · American · 2050 W Guadalupe Rd
• La Patrona Mexican Cuisine
  Restaurant · American · Latin American · 1526 E Main St
• Marie Callendar's
  Restaurant · American · 865 S Dobson Rd
• Mesa Grill Co
  Restaurant · American · 1800-1998 N 46th St.
• My Granny’s Banana Pudding Company
  Restaurant · American · Southern and soul food · 1941 W Guadalupe Rd Ste 118
• Old Country Buffet
  Restaurant · American · 1855 S Stapley Dr
• Pedrito's Mexican Food
  Restaurant · American · Latin American · 1940 E Broadway Rd
• Quiznos Subs
  Restaurant · American · 1950 E University Dr
• Ray's Pizza
  Restaurant · American · 1804 S Signal Butte Rd #10
• Village Inn
  Restaurant · American · Chain · 1859 S Stapley Dr Ste 107
• Village Inn
  Restaurant · American · Chain · 2034 E Southern Ave
• Village Inn
  Restaurant · American · Chain · 6813 E Main St
• Village Inn Restaurants
  Restaurant · American · Chain · 1155 S Dobson Rd
• Village Inn Restaurants
  Restaurant · American · Chain · 5961 E McKellips Rd
• Wingstock: Where Music and Chicken Meat
  Restaurant · American · 263 N Center St
• Zuni Grill
  Restaurant · American · 1011 W Holmes Ave
• Old School Grub
  Restaurant · American · 6810 E Main St
• Apache Wells Country Club
  Restaurant · American · 2709 N Higley Rd
• Habit Burger & Grill
  Restaurant · American · Chain
• Mother's Tamales
  Restaurant · American · Latin American · 1940 E Broadway Rd.
• The Resident
  Restaurant · American · 1011 W Holmes Ave
• Jim Bob's Burgers
  Restaurant · American · 218 W Main St
• Fat Willy's Pub &Grille
  Restaurant · American · 650 N Hawes
• Solutions Bar & Grill
  Restaurant · American · guadalupe and power rd

American elsewhere in Arizona

Among the Arizona cities in this guide, the most american listings are in Phoenix (216), Scottsdale (78), Tucson (65), Chandler (38), Tempe (34) and Glendale (20).

Run a american spot in Mesa?

You share this list with 55 other american listings. The ones guests reorder from are the ones that are easy to order from directly. Servestack gives you your own ordering site with zero commission, and Studio designs the menu, flyers and posts to go with it. Run your numbers with the commission savings calculator.

Place data from the Overture Maps Foundation (overturemaps.org), which includes data from Meta, Microsoft and Foursquare, used under the CDLA Permissive 2.0 and Apache 2.0 licenses. Restaurants open, close and move; check with the restaurant before you go. Data refreshed 2026-10-11.